GLUTASOME Cream is a medical-grade topical depigmenting formulation engineered to target the underlying cascades of melasma and recalcitrant hyperpigmentation without compromising the epidermal stratum corneum barrier.
By combining Tranexamic Acid (3%) to block plasminogen-induced melanocyte activation, Alpha Arbutin (2%) for competitive tyrosinase inhibition, stabilized Retinaldehyde for accelerated epidermal turnover, and a Ceramide Complex (NP/AP/EOP) with phytosphingosine, GLUTASOME Cream provides intensive melanin correction while actively fortifying lipid bilamellar membranes.
Primary Clinical Indications
Formulated to address specific dermatological indications requiring measurable physiological intervention:
- Epidermal, dermal, and mixed melasma resistant to conventional treatments.
- Post-inflammatory hyperpigmentation (PIH) following acne vulgaris or cosmetic interventions.
- Photo-aged dyschromia, solar lentigines, and age-related hyperpigmented macules.
- Compromised skin barrier with concomitant sensitivity and pigmentary instability.
Formulation Profile
Tranexamic Acid 3%, Alpha Arbutin 2%, Encapsulated Retinaldehyde, Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Cholesterol, Niacinamide 4%, Sodium Hyaluronate, Kojic Dipalmitate.
Recommended Administration & Dosage
Apply a pea-sized amount evenly over cleansed face and neck every morning and evening. For daytime use, always follow with broad-spectrum photoprotection (Aspida SPF 50+).
Aspida Advanced Sun Protection
Essential broad-spectrum SPF 50+ PA++++ shield to prevent UV-mediated melanogenesis rebound during depigmentation therapy.
View Monograph
Clinical Evaluation & Results
Visual aid clinical tracking demonstrates a 43% reduction in Melasma Area and Severity Index (MASI) scores over an 8-week span, with zero reported erythema or barrier rebound.
89%
Melasma & Spot Fading
Targeted inhibition of plasmin and tyrosinase enzyme activity.
96%
Ceramide Barrier Recovery
Replenishment of physiologic stratum corneum intercellular lipids.
91%
MASI Score Improvement
Clinically documented lightening of recalcitrant hyperpigmentation.